our lab

axolotl brain atlas

affiliations @ msu

Integrative Biology

selected publications

Hall KW, Eisthen HL, Williams BL. (2016) Proteinaceous pheromone homologs identified from the cloacal gland transcriptome of a male axolotl, Ambystoma mexicanum. PLOS ONE. doi: 10.1371/journal.pone.0146851

Eisthen HL, Theis KR (2015) Animal-microbe interactions and the evolution of nervous systems. Phil Trans Roy Soc B 371: 20150052. doi: 10.1098/rstb.2015.0052.

Williams BL, Akazome Y, Oka Y, Eisthen HL (2014) Dynamic evolution of the GnRH receptor gene family in vertebrates. BMC Evol Biol 14:215. doi:10.1186/s12862-014-0215-y.

Corfield JR, Eisthen HL, Iwaniuk AN, Parsons S (2014) Anatomical specialisations for enhanced olfactory sensitivities in kiwi, Apteryx mantelli. Brain Behav Evol 84:214-226. doi:10.1159/000365564.

Eisthen HL, Krause BC (2012) Ambiguities in the relationship between gonadal steroids and reproduction in axolotls (Ambystoma mexicanum). Gen Comp Endocrinol 176:472-480.

Kawai T, Oka Y, Eisthen HL (2009) The role of the terminal nerve and GnRH in olfactory system neuromodulation. Zool Sci 26: 669-680.

Eisthen HL, Schwenk K (2008) Chemical senses: The stimulus and its detection. In Sensory Evolution on the Threshold: Adaptations in Secondarily Aquatic Vertebrates (JGM Thewissen and S Nummela, eds), Univ California Press, Berkeley CA, pp 35-41.

Reiss JO, Eisthen HL (2008) Chemical senses: Comparative anatomy and physiology in amphibians. In Sensory Evolution on the Threshold: Adaptations in Secondarily Aquatic Vertebrates (JGM Thewissen and S Nummela, eds), Univ California Press, Berkeley CA, pp 43-63.

Mousley A, Polese G, Marks NJ, Eisthen, HL (2006) Terminal-nerve-derived neuropeptide Y modulates odorant responses in hungry animals. J Neurosci 26: 7707-7717.

Eisthen HL, Polese G (2006) Evolution of vertebrate olfactory subsystems. In Evolution of Nervous Systems, Vol 2: Non-mammalian Vertebrates (JH Kaas, ed), Academic Press, Oxford, pp. 355-406.

Baxi KN, Dorries KM, Eisthen HL (2006) Is the vomeronasal system really specialized for pheromone detection? Trends Neurosci, 29: 1-7.

Eisthen HL, Wyatt TD (2006) The vomeronasal system and pheromones. Curr Biol, 16: R73-74.

Eisthen HL, Park D (2005) Chemical signals and vomeronasal system function in axolotls (Ambystoma mexicanum). In Chemical Signals in Vertebrates 10 (R. Mason, M. LeMaster, and D. Müller-Schwarze, eds.), Springer Verlag, New York, pp 216-227.

Park D, Propper CR, Eisthen HL (2005) The pheromonal repelling response in red-spotted newts (Notophthalmus viridescens). In Chemical Signals in Vertebrates 10 (R Mason, M LeMaster, D Müller-Schwarze, eds), Springer Verlag, New York, pp 42-48.

Park D, McGuire JM, Majchrzak AL, Ziobro JM, Eisthen HL (2004) Discrimination of conspecific sex and reproductive condition using chemical cues in axolotls (Ambystoma mexicanum). J Comp Physiol A, 190: 415-427.

Park D, McGuire JM, Eisthen HL (2004) Differential responses of large and small male red-spotted newts, Notophthalmus viridescens, to conspecific chemical cues. Kor J Biol Sci, 8: 81-87.

Park D, Eisthen HL (2003) Gonadotropin releasing hormone (GnRH) affects odorant responses in the peripheral olfactory system of axolotls. J Neurophysiol, 90: 731-738.

Park D, Zawacki SR, Eisthen HL (2003) Olfactory signal modulation by molluscan cardioexcitatory tetrapeptide (FMRFamide) in axolotls (Ambystoma mexicanum). Chem Senses, 28: 339-348.

Eisthen HL (2002) Why are olfactory systems of different animals so similar? Brain Behav Evol, 59: 273-293.

Eisthen HL, Nishikawa KC (2002) Convergence: Obstacle or opportunity? Brain Behav Evol, 59: 235-239.

Eisthen HL (2000) Presence of the vomeronasal system in aquatic salamanders. Phil Trans Roy Soc (London), 355: 1209-1213.

Eisthen HL, Delay RJ, Wirsig-Wiechmann CR, Dionne VE (2000) Neuromodulatory effects of gonadotropin releasing hormone on olfactory receptor neurons. J Neurosci, 20: 3947-3955.

Eisthen HL (1997) Evolution of vertebrate olfactory systems. Brain Behav Evol, 50: 222-233.

Eisthen HL, Northcutt RG (1996) Silver lampreys (Ichthyomyzon unicuspis) lack a gonadotropin-releasing hormone- and FMRFamide-immunoreactive terminal nerve. J Comp Neurol, 370: 159-172.

Eisthen HL, Sengelaub DR, Schroeder DM, Alberts JR (1994) Anatomy and forebrain projections of the olfactory and vomeronasal organs in axolotls (Ambystoma mexicanum). Brain Behav Evol, 44: 108-124.