Skip to main content
Michigan State UniversityBreedlove Jordan lab at MSU

Kentaro Oki

Kentaro Oki

I received my Bachelor's of Science in Biology and a Chemistry minor from Indiana University-Bloomington in 2006. As an undergraduate, I became interested in hormonal actions, particularly their effects on behavior, anatomy, and physiology, and I began working under the guidance of Dr. Greg Demas to study the pineal hormone melatonin and its effects on aggression in female Siberian hamsters.

My current research focuses on possible myopathic contributions in spinal bulbar muscular atrophy (SBMA) or Kennedy's Disease, an X-linked disorder that selectively affects males and is characterized by progressive motor impairments. Although SBMA is commonly viewed as a motor neuron disease, we have recapitulated the disease where mice that selectively overexpress wild type androgen receptors in skeletal muscle fibers exhibit androgen-dependent motor deficits (i.e. males exhibit motor deficits but improve after castration, and females are asymptomatic until treated with testosterone). Some novel findings in our SBMA model make the research very exciting, but it is also enjoyable to me, personally, because my work combines all of my undergraduate interests (hormone actions, behavior, anatomy, and physiology) into one project.

My studies are conducted using a variety of techniques, such as behavior testing, gel analyses, and in vitro tissue preparations. If you have any questions about my research, please feel free to contact me.